Mathematical modeling approaches to understanding pain processing and chronic pain therapies
Wednesday, June 16 at 09:30am (PDT)Wednesday, June 16 at 05:30pm (BST)Thursday, June 17 01:30am (KST)
Jennifer Crodelle (Middlebury College, USA), Kevin Hannay (University of Michigan, USA), Victoria Booth (University of Michigan, USA)
Chronic pain affects approximately 20% of US adults and is one of the most common reasons adults seek medical care . Spinal-cord stimulation (SCS) is a widely used therapy to alleviate chronic pain. However, details of how pain is processed in the spinal cord and the mechanisms by which SCS modulates sensory signals from the periphery have not been completely determined. Recent mathematical modeling approaches have focused on illuminating these mechanisms. In this minisymposium, speakers will present diverse physiologically-based mathematical modeling studies addressing the processing of pain signaling in spinal-cord circuits, as well as modulation of that processing by SCS.  Dahlhamer J, Lucas J, Zelaya, C, et al. Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults — United States, 2016. MMWR Morb Mortal Wkly Rep 2018;67:1001–1006.