Hibernation and circadian rhythms: the differences and the possible interactions
Monday, June 14 at 7:45pm (PDT)Tuesday, June 15 at 03:45am (BST)Tuesday, June 15 11:45am (KST)
Shingo Gibo (RIKEN, Japan) and Gen Kurosawa (RIKEN, Japan)
Organisms living in a fluctuating environment have evolved physiological systems with various time-scales. For example, hibernators such as thirteen-lined ground squirrels, Syrian hamsters, and bears drastically decrease their body temperature and keep inactive during a season with little or no food. To our knowledge, fundamental cellular and molecular mechanisms of hibernation remain to be elusive. Meanwhile, organisms, including hibernators show daily rhythms which are often robust to external perturbations. Despite the progress of molecular studies for circadian rhythms, mechanism of the circadian period stable to temperature, is largely unknown. Toward understanding hibernation and circadian rhythms, mathematical biology can play various roles, including (1) quantification of experimental data, (2) modelling and simulation of biological systems, and (3) proposing molecular mechanisms. In this mini-symposium, we invite experimental and mathematical biologists studying hibernation and circadian rhythms. Through the discussions between the speakers and audiences, we wish to consider the differences and the possible interactions between hibernation and circadian rhythms. We also wish to consider a possible new direction of collaborations between experimental and mathematical biology toward understanding the phenomena.