Modeling and Simulation of Hydrodynamics in Cell Biology
Wednesday, June 16 at 05:45pm (PDT)Thursday, June 17 at 01:45am (BST)Thursday, June 17 09:45am (KST)
Thomas Fai (Brandeis University, USA), Ying Zhang (Brandeis University, USA)
Hydrodynamics are ubiquitous in living organisms and influence many cellular properties and processes, including intracellular processes, reaction kinetics and cell-cell signaling cascade. Participants in this mini-symposium present research on the role of hydrodynamics across different scales ranging from the subcellular to single cell to collections of cells. At the subcellular scale, fluid dynamics are key in the organization of the intracelluar machinery for cell division and for the trafficking of proteins in the cell membrane. On the single cell level, cells sense and respond to the dynamic fluid environments in development, angiogenesis, and bone remodeling. On larger scales, the mechanics of suspensions of cells and how they interact with surfaces is important for the function of the circulatory system and in measurements using flow cytometry. To study these fluid-structure interaction problems, mathematical models involving deterministic or stochastic PDEs are combined with numerical methods such as the immersed boundary method.