Bacterial swarming is a mode of motion in which dense collectives of rod-shaped flagellated cells migrate rapidly on surfaces. The transition into swarming involves several cellular processes, including changes in cell aspect ratio, suggesting that bacteria manipulate these properties in order to promote physical conditions that are favorable for swarming. New results with monolayer swarms of Bacillus subtilis with different aspect ratios were analyzed at different cell-densities. A comprehensive analysis of the individual and collective dynamics of bacteria in a swarm brings forth a phase diagram, showing sharp transitions between phases corresponding to qualitatively different swarm statistics. From a biological perspective, we find that under standard conditions bacteria inhabit a region of phase space in which the swarm dynamics is highly robust and insensitive to fluctuations. In this regime, bacteria do not form very large clusters and lack global orientational order, properties which may reduce the colony's ability to expand rapidly in the absence of external directional cues.

# Complex Biological and Biomedical Systems Subgroup (CBBS)

###### Jump to:

# Sub-group minisymposia

##### MS01-CBBS:

Mathematical modeling of emergent phenomena in cell colonies

**Organized by:** Shawn D. Ryan (Cleveland State University, United States), Mykhailo Potomkin (UC Riverside, United States), Jia Gou (UC Riverside, United States)

Note: this minisymposia has multiple sessions. The second session is **MS02-CBBS**.

**Gil Ariel***(Bar Ilan University, Israel)*

"A Phase Diagram for Bacterial Swarming"**Fernando Peruani***(CY Cergy Paris University, France)*

"A mathematical approach to bacterial infections: models for bacterial exploration, aggregation, and infection"**Silke Henkes***(University of Bristol, United Kingdom)*

"Flow, fluctuate, freeze: Cell sheets as soft active matter"**Kevin Painter***(Politecnico di Torino, Italy)*

"Sticking together by going against the flow"

##### MS02-CBBS:

Mathematical modeling of emergent phenomena in cell colonies

**Organized by:** Shawn D. Ryan (Cleveland State University, United States), Mykhailo Potomkin (UC Riverside, United States), Jia Gou (UC Riverside, United States)

Note: this minisymposia has multiple sessions. The second session is **MS01-CBBS**.

**Shawn D. Ryan***(Dept. of Mathematics and Statistics, Cleveland State University, United States)*

"Role of hydrodynamic interactions in collective swimming of bacteria"**Paul Kulesa***(Stowers Institute for Medical Research, United States)*

"Coupling Invasion and Collective Migration of the Embryonic Neural Crest"**Brian Camley***(Johns Hopkins University, United States)*

"Collective cell migration on patterns with topological defects"**Wouter-Jan Rappel***(UC San Diego, United States)*

"Modeling the collective motion of amoebae"

##### MS03-CBBS:

Mathematics of Biochemical Reaction Networks

**Organized by:** Matthew Johnston (Lawrence Technological University, United States), Angelyn Lao (De La Salle University, Phillipines)

**Matthew Johnston***(Lawrence Technological University, United States)*

"Analyzing Steady States of Mass Action Systems through Network Splitting"**Editha Jose***(University of the Philippines Los Banos, Philippines)*

"Absolutely complex balanced power law kinetic systems"**Polly Yu***(University of Wisconsin-Madison, United States)*

"Conditions for stability of mass-action systems"**Bryan Hernandez***(University of the Philippines Diliman, Philippines)*

"Independent Decompositions of Chemical Reaction Networks and Some Applications"

##### MS05-CBBS:

Data-driven approaches to understanding collective behavior

**Organized by:** Maria Bruna (University of Cambridge, United Kingdom), Ulrich Dobramysl (University of Cambridge, United Kingdom), Simon Garnier (New Jersey Institute of Technology, USA)

**Meg Crofoot***(Max Planck Institute of Animal Behavior & University of Konstanz, Germany)*

"Locomotor compromise underlies coordination in heterogeneous groups on the move"**Colin Torney***(School of Mathematics & Statistics, University of Glasgow, United Kingdom)*

"Inferring microscale properties of interacting systems from macroscale observations"**Yuko Ulrich***(Institute of Integrative Biology, ETH Zurich, Switzerland)*

"Behavioral organization in heterogeneous groups of a social insect"**Adrien Blanchet***(Toulouse School of Economics, France)*

"Mathematical model of disinformation"

##### MS06-CBBS:

Exploring the processes of bacteria self-organization using mathematical modelling and experimental studies

**Organized by:** Diane Peurichard (Inria Paris, France), Marie Doumic (Inria Paris, France)

**Nicolas Desprat***(Laboratoire de Physique de l’École normale supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université de Paris, 75005 Paris, France)*

"Mutliscale morphogenesis of bacterial microcolonies"**Sophie Hecht***(Inria Paris, France)*

"On the modelling of the morphogenesis of rod-shaped bacteria micro-colony."**Laura Kanzler***(Laboratoire Jacques-Louis Lions, Sorbonne Université, France)*

"Kinetic Modelling of Myxobacteria"**Marc Hoffmann***(INRIA, Mamba team & University Paris-Dauphine, France)*

"Statistical estimation of the interaction kernel in McKean-Vlasov model in a mean-field limit"

##### MS07-CBBS:

Wave propagation and pattern formation phenomena in biological models

**Organized by:** Bogdan Kazmierczak (Institute of Fundamental Technological Research, Polish Academy of Sciences, Poland), Je-Chiang Tsai (Department of Mathematics, National Tsing Hua University, Taiwan)

**Hirofumi Izuhara***(University of Miyazaki, Japan)*

"On the spreading front arising in mathematical models of population dynamics"**Dariusz Wrzosek***(University of Warsaw, Poland)*

"Chemical signalling and pattern formation in predator-prey models"**Tomasz Lipniacki***(Institute of Fundamental Technological Research, Polish Academy of Sciences, Poland)*

"Traveling and standing fronts on curved surfaces"**Tilmann Glimm***(Western Washington University, USA)*

"Modeling interplay of pattern formation and cell phenotype transitions during limb cartilage formation"

##### MS08-CBBS:

Waves and traveling phenomena in living systems

**Organized by:** Stephanie Dodson (University of California, Davis, United States), Scott McCalla (Montana State University, United States)

**Stephanie Dodson***(University of California, Davis, United States)*

"One-dimensional spiral waves and reflection-induced cardiac arrhythmia"**Matt Holzer***(George Mason University, United States)*

"Locked fronts in a discrete time discrete space population model"**Tracy Stepien***(University of Florida, United States)*

"Traveling Waves of a Go-or-Grow Model of Glioma Growth"**Scott McCalla***(Montana State University, United States)*

"Nonlocal interfacial dynamics in biological systems"

##### MS09-CBBS:

Modeling and data analysis of dynamics from molecules, cells to populations

**Organized by:** Lei Zhang (Peking University, China)

Note: this minisymposia has multiple sessions. The second session is **MS10-CBBS**.

**Hao Ge***(Peking University, China)*

"The Nonequilibrium Mechanism of Noise-Enhanced Drug Synergy in HIV Latency Reactivation"**Yusuke Imoto***(Kyoto University, Japan)*

"Topological Trajectory Inference for Single-cell RNA Sequencing Data"**Suoqin Jin***(University of California Irvine, U.S.)*

"Understanding the role of cell-cell communication in cell fate decisions from single-cell data"**Dae Wook Kim***(Korea Advanced Institute of Science and Technology, Korea)*

"Moment-based inference of cell-to-cell variability in signal transduction time"

##### MS10-CBBS:

Modeling and data analysis of dynamics from molecules, cells to populations

**Organized by:** Lei Zhang (Peking University, China)

Note: this minisymposia has multiple sessions. The second session is **MS09-CBBS**.

**Lei Zhang***(Peking University, China)*

"Computable Early C. elegans Embryo with a Data-driven Phase Field Model"**Masakazu Akiyama***(Meiji University, Japan)*

"A three-dimensional vertex dynamics model for understanding the twisting phenomenon of the hindgut of Drosophila"**Chunhe Li***(Fudan University, China)*

"A Dimension Reduction Approach for Energy Landscape"**Chansoo Kim***(Korea Institute of Science and Technology, Korea)*

"Kinetic Monte Carlo and the infectious disease dynamics with age and region"

##### MS11-CBBS:

Recent advances in random and deterministic modeling in biology/health sciences

**Organized by:** Maria C.A. Leite, (University of South Florida St.Petersburg), Juan Carlos Cortés López (Instituto Universitario de Matemática Multidisciplinar. Universitat Politècnica de València, Spain), Rafael J. Villanueva Micó (Instituto Universitario de Matemática Multidisciplinar. Universitat Politècnica de València, Spain)

Note: this minisymposia has multiple sessions. The second session is **MS17-CBBS**.

**Óscar Angulo***(Universidad de Valladolid, Spain)*

"Numerical integration of an age-structured model with unbounded age-domain"**Carla Pinto***(School of Engineering, Polytechnic of Porto, Portugal)*

"Modified SIQR model for the COVID-19 outbreak"**Clara Burgos***(Instituto Universitario de Matemática Multidisciplinar. Universitat Politècnica de València, Spain)*

"A computational procedure describe breast tumor growth capturing the uncertainty in the volume data"**Gilberto Gonzalez-Parra***(Department of Mathematics, New Mexico Tech, USA)*

"Mathematical modeling of COVID-19 pandemic under social behavior uncertainty (Pre-recorded)"

##### MS12-CBBS:

Lattice Models and Agent-Based Models in Biology: Linking Individual Properties to Population Properties

**Organized by:** Bhargav Karamched (Florida State University, United States of America)

Note: this minisymposia has multiple sessions. The second session is **MS13-CBBS**.

**Bhargav Karamched***(Florida State University, United States of America)*

"Spatial Model of Oncolytic Virotherapy: Targeting Drug-Resistant Mutants"**Cicely Macnamara***(University of St Andrews, Scotland)*

" Computational modelling and simulation of tumour growth and development within a 3D heterogeneous tissue"**Hamid Teimouri***(Rice University, United States of America)*

"The impact of the temporal order of mutations on cancer initiation dynamics"**Namiko Mitarai***(University of Copenhagen, Denmark)*

"Emergence of diversity in a model ecosystem of sessile species with mutually exclusive interactions"

##### MS13-CBBS:

Lattice Models and Agent-Based Models in Biology: Linking Individual Properties to Population Properties

**Organized by:** Bhargav Karamched (Florida State University, United States of America)

Note: this minisymposia has multiple sessions. The second session is **MS12-CBBS**.

**Tom Chou***(University of California - Los Angeles, United States of America)*

"RNA polymerase and ribosome interactions in transcriptional error correction and translation-transcription coupling"**Claudia Neuhauser***(University of Houston, United States of America)*

"Fighting Cancer with Viruses--Mathematical Models to Guide Therapy"**James Glazier***(Indiana University, United States of America)*

"Multicellular modeling of viral infection and immune response in epithelial tissues and response to drug therapy"**Joanna Wares***(University of Richmond, United States of America)*

"Developing a computational modeling course in the time of COVID-19"

##### MS14-CBBS:

Understanding lung function and disease through mathematical modeling and experiment

**Organized by:** Uduak George (San Diego State University, United States), Mona Eskandari (University of California Riverside, United Staes)

Note: this minisymposia has multiple sessions. The second session is **MS15-CBBS**.

**Hannah Pybus***(School of Mathematical Sciences, University of Nottingham, United Kingdom)*

"Airway constriction in asthma - is it the chicken or the egg?"**Ashley Schwartz***(Computational Science Research Center, San Diego State University, United States)*

"New metrics for quantifying the spatial inhomogeneity of abnormal fluid in MR images of cystic fibrosis lungs"**Nourridine Siewe***(Rochester Institute of Technology, United States)*

"A Mathematical Model of the Role of MIF in Severe Malarial Anemia: What Happens in TB"**Blessing Emerenini***(Rochester Institute of Technology, United States)*

"Trends in the mathematical modeling of Bacteria-Phage combat in lung treatment"

##### MS15-CBBS:

Understanding lung function and disease through mathematical modeling and experiment

**Organized by:** Uduak George (San Diego State University, United States), Mona Eskandari (University of California Riverside, United Staes)

Note: this minisymposia has multiple sessions. The second session is **MS14-CBBS**.

**Ariel Nikas***(Emory University, School of Medicine, United States)*

"Using morphoelasticity to model early lung branching"**Mona Eskandari***(University of California at Riverside, United States)*

"Characterizing pulmonary mechanics using an experimental-computational framework"**Ramana Pidaparti***(University Of Georgia Athens, United States)*

"Computational Models and Informatics for Lung Inflammation and Aging"**Uduak George***(San Diego State University, United States)*

"Mathematical modeling of fibroblast growth factor expression in developing lungs"

##### MS17-CBBS:

Recent advances in random and deterministic modeling in biology/health sciences

**Organized by:** Maria C.A. Leite, (University of South Florida St.Petersburg), Juan Carlos Cortés López (Instituto Universitario de Matemática Multidisciplinar. Universitat Politècnica de València, Spain), Rafael J. Villanueva Micó (Instituto Universitario de Matemática Multidisciplinar. Universitat Politècnica de València, Spain)

Note: this minisymposia has multiple sessions. The second session is **MS11-CBBS**.

**Francisco Rodríguez***(Dept. of Applied Mathematics and Multidisciplinary Institute for Environmental Studies (IMEM), University of Alicante, Spain)*

"Ecohydrological feedbacks, delay responses and random perturbations in mean field dryland vegetation models"**Sandra Delgadillo***(Universidad Autónoma de Aguascalientes, México)*

"Full probabilistic analysis of random first-order linear differential equations with Dirac delta impulses (Pre-recorded)"**Carlos A. Braumann***(Department of Mathematics & CIMA, Universidade de Évora, Portugal)*

"Harvesting optimization in a randomly varying environment"**Roberto Ku-Carrillo***(Universidad Autónoma de Aguascalientes, Mexico)*

"On a linear random differential equation with periodic harvesting and migration"

##### MS18-CBBS:

Stochastic methods for biochemical reaction networks

**Organized by:** Wasiur KhudaBukhsh (The Ohio State University, United States), Hye-Won Kang (University of Maryland at Baltimore County, United States)

Note: this minisymposia has multiple sessions. The second session is **MS19-CBBS**.

**Ankit Gupta***(ETH Zurich, Switzerland)*

"A deep learning approach for solving chemical master equations"**Grzegorz Rempala***(The Ohio State University, United States)*

"Approximating bio-chemical dynamics using survival models"**Jinsu Kim***(University of California Irvine, USA)*

"Mixing times for stochastically modeled biochemical reaction systems"**Wasiur KhudaBukhsh***(The Ohio State University, United States)*

"Chemical reaction networks with covariates"

##### MS19-CBBS:

Stochastic methods for biochemical reaction networks

**Organized by:** Wasiur KhudaBukhsh (The Ohio State University, United States), Hye-Won Kang (University of Maryland at Baltimore County, United States)

Note: this minisymposia has multiple sessions. The second session is **MS18-CBBS**.

**David Anderson***(University of Wisconsin Madison, USA)*

"Time-dependent product-form Poisson distributions for reaction networks"**Lea Popovic***(Concordia University, Canada)*

"Stochastic reduction of spatially heterogeneous biochemical reaction networks"**Hye-Won Kang***(University of Maryland at Baltimore County, United States)*

"Stochastic modeling of metabolic enzyme complexes"**Felipe Campos***(University of California, San Diego, USA)*

"Error bounds for the one-dimensional constrained Langevin approximation for density-dependent Markov chains"

##### MS20-CBBS:

WiMB: Mathematical modeling and its application

**Organized by:** Qimin Huang (Case Western Reserve University, USA), Katie Storey (University of Michigan, USA)

**Atanaska Dobreva***(Arizona State University, USA)*

"Investigating pathological mechanisms in cone photoreceptor vitality and the timing of rescue strategies via bifurcation analysis and time-varying sensitivity analysis"**Katie Storey***(University of Michigan, USA)*

"A Framework for Performing Data-Driven Modeling of Tumor Growth with Radiotherapy Treatment"**Qimin Huang***(Case Western Reserve University, USA)*

"Investigating the impact of combination phage and antibiotic therapy: A modeling study"**Hwayeon Ryu***(Elon University, USA)*

"Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization"

# Sub-group contributed talks

##### CT01-CBBS:

CBBS Subgroup Contributed Talks

**Jolene Britton***University of California, Riverside*

"A Metabolism-Based Multiscale Model of Fungal Development and Growth"**Brenda Lyn A. Gavina***University of the Philippines*

"Optimization of dosing strategy for anovulation"**Daniel Plaugher***University of Kentucky*

"Modeling the Pancreatic Cancer Microenvironment in Search of Control Targets"**Furkan Kurtoglu***Indiana University*

"Integration of Intracellular Kinetic Models to Multiscale Agent-Based Models"

##### CT02-CBBS:

CBBS Subgroup Contributed Talks

**Anushaya Mohapatra***BITS, Pilani, Goa Campus, India*

"The ideal free distribution and the evolution of partial migration"**Debasmita Mukherjee***Sunandan Divatia School of Science, SVKM's NMIMS Deemed to be University, Mumbai, India*

"Atherosclerosis: A Mathematical Model for Early Prognosis"**Michael Getz***Indiana University, Bloomington*

"Continuum to Discrete event modeling within PhysiCell"**Raneem Aizouk***City, university of London*

"Modelling conflicting individual preferences: target sequence and graph realization"

##### CT03-CBBS:

CBBS Subgroup Contributed Talks

**David Lacoste***Laboratory Gulliver, ESPCI, Paris*

"Emergence of homochirality in large molecular systems"**Martijn de Jong***Leiden University*

"Cellular Potts model of convergent extension can explain shape variability of gastruloids"**Robert Planque***Vrije Universiteit Amsterdam*

"Stability of a reaction pathway adaptively controlled to maximise flux"**Bime Markdonal Ghakanyuy***University of Buea, Cameroon*

"Investigating the Impact of Multiple Feeding Attempts on Mosquito Dynamics via Mathematical Models"

##### CT04-CBBS:

CBBS Subgroup Contributed Talks

**Xueying Wang***Washington State Univeristy*

"Impact of Varying Networks on Disease Invasion"**Shaza Alsibaai***Department of Mathematics & Statistics, McGill University, Montréal, Canada.*

"The Necessity of Including a Sub-model for Iron Metabolism in Mathematical Modelling of Erythropoiesis"**Gess Iraji***Brandeis University*

"Mathematical Modeling of Clogging in Microfluidic Structures from Simple to Complex Geometries"

##### CT05-CBBS:

CBBS Subgroup Contributed Talks

**Donggu Lee***Konkuk University*

"Role of OCT1 in regulation of miR-451-LKB1-AMPK-OCT1-mTOR core signaling network and cell invasion in glioblastoma"**Yukitaka Ishimoto***Akita Prefectural University*

"In-vivo cell flow visualisation using deep learning and other means"**Tara Hameed***Imperial College London*

"A systematic workflow to assess the useability of data in model development"**Anibal Thiago Bezerra***Instituto de Ciências Exatas, Universidade Federal de Alfenas*

" Gastric Emptying and Orocaecal Transit Analyses of Diabetic and Control Individuals Through Deep Neural Networks"

##### CT06-CBBS:

CBBS Subgroup Contributed Talks

**Helen Zha***University of Oxford*

"Lubrication model of a valve-controlled, gravity-driven bioreactor for platelet production"**Sahar Jafari Nivlouei***Department of Physics, University of Coimbra, Portugal*

"3D Multiscale Modeling of Tumor Vascular Growth: Evaluation of the effectiveness of chemotherapy"**Richard Foster***Virginia Commonwealth University*

"Modeling Breathing Asynchrony in the Preterm Infant"**Alberto Coccarelli***College of Engineering, Swansea University*

"Computer modelling for decrypting vascular function"

##### CT07-CBBS:

CBBS Subgroup Contributed Talks

**Anna Claudia Mello de Resende***Laboratório Nacional de Computação Científica (LNCC)*

"Integrating Image-Driven Deformation with Tumor Growth Models"**Dorsa Mohammadrezaei***Department of Applied Mathematics, University of Waterloo, Waterloo, Canada*

"In-vitro and In-silico Study on a 3D-Bioprinted Breast Cancer Tumor Model"**Noemi Andor***Moffitt Cancer Center*

"Tipping cancer cells over the edge; the context-dependent cost of DNA content variation"**Anna Miller***Department of Integrated Mathematical Oncology, Moffitt Cancer Center*

"An integrated computational model of multiple myeloma-bone dynamics under treatment"

##### CT09-CBBS:

CBBS Subgroup Contributed Talks

**Prasenjit Ghosh***PhD Candidate, Indian Institute of Science, Bengaluru, India*

"Discrete particulate modeling of cell nuclei"**Benjamin Wölfl***University of Vienna, Vienna Graduate School of Population Genetics*

" On branch length distributions in the coalescent and its application in the i-ton density score"**Diego Samuel Rodrigues***FT-UNICAMP*

"A Bayesian Framework for Mathematical Modeling of In Vivo Pharmacokinetic Profiles of Magnetic Particles"**Jackie Taylor***University of Minnesota, Twin Cities*

" An advection-diffusion-aggregation model for the colony formation and vertical motility of Microcystis aeruginosa"

# Sub-group poster presentations

##### CBBS Posters